Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Utilized in the procedure of numerous myeloma. Its synthesis or research is crucial for ensuring the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to treat breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast cancer. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): N-Pyrazinylcarbonyl-L-phenylalanine A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Utilized in food stuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate CAS NO.152460-10-1 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).